GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2275426 | 1 | rs1707304 | chr1:46598269 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.76 | 1.02E-7 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs1707321 | chr1:46505309 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs1707335 | chr1:46571921 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs1707336 | chr1:46493460 | CCDC163P | chr1:45960581-45965646:- | -0.48 | -6.01 | 3.45E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs1707340 | chr1:46514942 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2239557 | 1 | rs17096228 | chr14:74558669 | LIN52 | chr14:74551656-74667117:+ | 0.39 | 7.16 | 1.73E-10 | Common traits (Other) |
| THYM | cis | rs67366981 | 1 | rs17105547 | chr14:77698358 | NGB | chr14:77731834-77737655:- | -0.41 | -4.16 | 7.04E-5 | Obsessive-compulsive symptoms |
| THYM | cis | rs2066819 | 1 | rs17118439 | chr12:56667604 | RPS26 | chr12:56435686-56438005:+ | 0.79 | 4.16 | 6.91E-5 | Psoriasis vulgaris |
| THYM | cis | rs12780845 | 1 | rs17140062 | chr10:17202840 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.8 | 5.85E-6 | Homocysteine levels |
| THYM | cis | rs2077224 | 1 | rs17145874 | chr11:62195344 | ASRGL1 | chr11:62104774-62160885:+ | -0.29 | -4.41 | 2.74E-5 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2243480 | 1 | rs1715235 | chr7:65488394 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs11723261 | 1 | rs17164747 | chr4:260587 | ZNF718 | chr4:53272-156488:+ | 0.65 | 7.31 | 8.46E-11 | Immune response to smallpox vaccine (IL-6) |
| THYM | cis | rs17164851 | 1 | rs17164851 | chr7:130003487 | CPA5 | chr7:129984630-130008571:+ | 0.92 | 8.55 | 2.09E-13 | Age-related hearing impairment (interaction) |
| THYM | cis | rs9815354 | 1 | rs1716642 | chr3:41965865 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.59 | 6.88E-20 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs1716644 | chr3:41968028 | ULK4 | chr3:41288091-42003660:- | -0.96 | -10.38 | 2.59E-17 | Diastolic blood pressure |